Scientific Program

October 15
Session 1 – Energy Metabolism and Homeostasis

13:30 Opening
14:00-15:00 Opening Lecture: “Mitochondria, Diets, and the Regulation of Energy Metabolism” – Alicia Juliana Kowaltowski, PhD – USP
15:00–15:50 – Lecture 1 – “Is Cholesterol Good or Bad for Your Brain?” Jade de Oliveira, PhD – UFRGS

15:50–17:20 – Coffee Break & Poster Session 1

Oral Presentations 
17:20 – Vinícius Grippa (Master Student, PPGBQA UFSC)- Sleep perturbation during development alters glucose, lipid, and metabolomic profiles in rats.
17:35 – Christian Limberger (PhD Student, UFRGS) – Genetic influence of ido1 polymorphisms on brain hypometabolism and cognitive decline.

17:50–18:40 – Lecture 2 – “Central Mechanisms of Energy Balance Control” – Lício Augusto Veloso, PhD – UNICAMP

October 16
Session 2 – Molecular Pathways Linking Metabolism, Development, and Disease

8:30–9:20 – Lecture 3 – “The Surprising Functions of Adipocyte Extracellular Vesicles” – Clair Crewe, PhD – Washington University School of Medicine in St. Louis (USA).
9:20–10:10 – Lecture 4 – “B-cells, antibodies, and microbiome in the control of thermoregulation” – Luiz Osório Leiria, PhD – USP

10:10–10:40 – Coffee Break

Oral Presentations 
10:40– Giovanna Tassinari
(PhD student PPGBQA/UFSC). Impaired mitophagy and reduced AMPK activation due to glucotoxicity.
10:55– Camila Vieira Pinheiro (postdoc UFRGS). Disruption of mitochondrial homeostasis and communication between mitochondria and lysosomes in MPS I and II knockout models.

11:10–12:00 – Lecture 5 –“When Physics and Chemistry Meet Biology: Phase Transitions of the Prion Protein in Health and Disease” – Yraima Cordeiro, PhD – UFRJ

Lunch

14:00–14:50 – Lecture 6 – “Histone Lactylation Couples Cellular Metabolism with Developmental Gene Regulatory Networks” – Marcos Simões-Costa, PhD – Harvard University (USA).
14:50–15:40 – Lecture 7 – “Schizophrenia from a Proteomics Perspective” – Daniel Martins-de-Souza, PhD – UNICAMP

15:40–17:10 – Coffee Break & Poster Session

Oral Presentations
17:10- Pedro Quartiero Marmontel
(Master student, UFRGS). Molecular signature analysis in autism spectrum disorder and bipolar disorder: a translational approach between cellular biology and therapeutics. 
17:25- Eloiza Adriane Dal Molin
(PhD student, PPGBQA UFSC). Gene expression profiles of glucocorticoid exposure in human iPSC-derived neural models.

17:40–18:30 – Lecture 8 – “Molecular Mechanisms Underlying Accelerated Epigenetic Aging in Bipolar Disorder” Gabriel R. Fries, PhD – UTHealth, Houston (USA)

October 17
Session 3 – Toxicological Research

8:30–9:20 – Lecture 9 – Neurotoxicity Testing in Caenorhabditis elegans: New Applications within the Adverse Outcome Pathway” – Mirian B. Virgolini – National, University of Córdoba (Argentina)
9:20–10:10 – Lecture 10 – “Detecting the impact of contaminants in cetaceans: biomarker applications in whales and dolphins” – Karim H. Lüchmann, PhD –UDESC

10:10–10:40 – Coffee Break

Oral Presentations

10:40- Carmem Lucia Sperlich (PhD student, PPGBQA UFSC). Interplay between ferroptosis and dopaminergic cell death: a focus on the role of ferritin and exogenous fatty acids.
10:55- Barbara dos Santos (PhD student, PPGBQA UFSC). NRF2 Inhibition Sensitizes KEAP1-Mutant Lung Cancer Cells to PARP Inhibitor.
11:10 – Aline Barbosa Lima (PhD student, Farmacologia, UFSC).  When formulation matters: ROUNDUP®, unlike glyphosate alone, attenuates insulin secretion in pancreatic islets.

Lunch

Oral presentations: 13:30– Ana Paula da Silva Wives (Biotecnologia, UFRGS). Minocycline ameliorates cognitive impairments without modulating microglial: reactivity in sporadic hypercholesterolemia: a sex-specific analysis in mice.
13:45–Giuseppe de Rossi Faraco (Nutrição, UFSC). Protective effects of caffeine on adiposity and glucose homeostasis in high-fat diet-fed C57BL/6 mice.
14:00– Leonardo Viana de Lima (Biologia, UFSC). Early-life exposure to the viral mimetic poly(i:c) triggers sex-specific behavioral and hippocampal metabolic alterations in C57BL/6 mice.

14:15– 15:05 – Lecture 11 – “The Promising Model Amphipod Parhyale hawaiensis: From EVO-DEVO to Ecotoxicology” Gisela de Aragão Umbuzeiro, PhD – UNICAMP
15:05–15:55 – Lecture 12 – “Expression of Zebrafish Cytochrome P450 enzymes and the use of high throughput screening to discover their functions – Joanna Wilson, PhD – McMaster University (Canada)
15:55 – Closing Remarks